In-house members
15
Total footprint
30,000sq ft
Our Old Market incubator hosts growing Deep Tech companies that have moved beyond proof of concept and are scaling their teams, typically 20–30 people strong.
This site serves as the main event venue of our Bristol campus — featuring the 1023 bar, our community’s main stage for events and a gathering spot for informal meetups every Thursday.
Old Market members are breaking new ground in several science and engineering fields — from advanced sustainable materials to vaccine platforms and stem cell therapeutics.
With 30,000 sq ft of laboratory, office and meeting space, our Old Market incubator is a supportive, well-connected hub for growing Deep Tech companies.
This location also features a large event space, shared social spaces, and our favourite addition — the 1023 bar, open every Thursday for the community.
Membership includes access to our platform of support, providing opportunities to attend workshops and events, connect with other founders, and find a mentor.





Our Old Market incubator is currently full, but if you if you are looking for private lab space we encourage you to get in touch to enquire about future openings, or explore OMX, our third Bristol incubator, set to open in 2026.



Travel between locations is measured in walking distance
Midland Rd & St Philips Rd
0.5 miles / 11 min
0.7 miles / 15 min

Fine Agrochemicals is enhancing crop quality for fruit and flower growers in agricultural, ornamental and landscape markets using its plant growth regulator (PGR) technology. Its PGR products, made using naturally occurring molecules through fermentation and combined with chemically synthesised compounds, help stimulate plant cells to enhance nutrient levels and targeted growth for improved crop outputs.

Transdermal Diagnostics is pioneering the development of bio-wearables that enhance the prevention, diagnosis and management of chronic conditions like diabetes. Its unique sensing technology aims to create the world’s first needle-free continuous monitor for glucose and other health biomarkers. By analysing hair follicles, the adhesive skin patch and transmitter wirelessly communicate information straight to a smartphone app, facilitating a transformative shift in patient care and quality of life for those with diabetes.

Carbometrics is striving to improve diabetes patient care by enhancing technology for continuous glucose monitoring. The team aims to pave the way for a new class of highly-accurate sensors with its groundbreaking synthetic molecule that is both chemically stable and able to bind to glucose in the blood. This follows on from the work of exited startup Ziylo Ltd, which was Science Creates’ very first resident and acquired by Novo Nordisk in 2018.




EnsiliTech is improving the shelf-life and global accessibility of vaccines and other biological therapeutics by combatting cold chain transport and storage issues. Its novel ensilication technology, designed for both existing and new biopharmaceutical formulations, encases thermally unstable biomolecules within silica nanoshells to prevent environmental degradation. This eliminates the need for cold chain requirements that are expensive, prone to failure and generate significant carbon dioxide emissions.

Argonaute RNA is developing safe, reliable and targeted methods of temporarily silencing genes in different tissue cells. It does this via the proprietary modification of small interfering RNA (siRNA), using a novel stabilisation method to overcome previous obstacles to developing siRNA drugs for healthcare.

Anaphite is decarbonising battery production by accelerating the electric vehicle (EV) industry’s shift to dry battery electrode coating. Its technology platform solves the challenges of dry mixing and manufactures film-forming dry powders called Dry Coating Precursor (DCP®). This process enables cell manufacturers to reduce their energy use by up to 30% and create better, more sustainable batteries at lower cost.




Epinal is revolutionising the detection and prevention of narcotic-impaired behaviour for safer roads, flights and workplaces. Utilising AI and novel biotechnology that mimics natural sensory mechanisms, it’s developing a handheld breathalyser that generates rapid results with extreme sensitivity and selectivity.

Glaia is developing innovative solutions to optimise agricultural plant performance to help food security and fight climate change. Using disruptive technology, its sustainable agrochemicals unlock the potential of the photosynthetic process, enabling plant cells to more efficiently convert energy to biomass to increase crop yields without increasing inputs. This results in greater profits for growers and reduced greenhouse emissions, delivering more sustainable global food production.

neo-fossil is developing new technology using cell engineering to help reverse the threat of climate change. By optimising biology, it is creating new fossils that harvest atmospheric carbon dioxide, storing it for centuries.


